Modeling of Multifrequency Infrared Multiphoton Dissociation for Laser Isotope Separation.

Infrared multiphoton dissociation of two perfluorobutenes

Electron Detachment Dissociation and Infrared Multiphoton Dissociation of Heparin Tetrasaccharides.

Heparin glycosaminoglycans (GAGs) present the most difficult glycoform for analytical characterization due to high levels of sulfation and structural heterogeneity. Recent contamination of the clinical heparin supply and subsequent fatalities has highlighted the need for sensitive methodologies of analysis. In the last decade, tandem mass spectrometry has been increasingly applied for the analy...

Isotope effects and bond softening in intense-laser-field multiphoton dissociation of H2+

Isotope efFects in the Hz+-Dz+ fragmentation by intense laser fields o6er the possibility of a multiphoton interpretation of the bond-softening mechanism. Surprisingly, the calculations indicate that the one-photon dissociation of D&+ is favored with respect to that of H&+. This cannot be understood, as has previously been done, by a single-photon mechanism following tunneling through a lowered...

Laser isotope separation of uranium

A research effort was carried out at the Bhabha Atomic Research Centre (BARC), Mumbai, for developing laser-based techniques for enrichment of natural uranium to reactor-grade (2.5% to 3.0% U), with the potential to be economically scalable to industrial production. Three approaches – two molecular, namely CO2 laser-based approach and UF6-based approach, and one atomic, namely Atomic Vapour Las...

Combined Infrared Multiphoton Dissociation with Ultraviolet Photodissociation for Ubiquitin Characterization

Herein we report the successful implementation of the consecutive and simultaneous photodissociation with high (213 nm) and low (10.6 μm) energy photons (HiLoPD, high-low photodissociation) on ubiquitin in a quadrupole-Orbitrap mass spectrometer. Absorption of high-energy UV photon is dispersed over the whole protein and stimulates extensive C-Cα backbone fragmentation, whereas low-energy IR ph...